Infectious Diseases

Infectious diseases are illness caused by external organisms known as pathogens as opposed to diseases caused by genetics, aging, or the environment. As the name suggests, you can get an infectious disease when you are infected by pathogens in contrast to non-infectious disease like cancer, Alzheimer’s disease, and diabetes. Depending on the pathogen and disease, you can further pass on the illness to another person. Not all infectious disease spreads from person to person but those that do are known as communicable disease.

The most common infectious agents are made up of pathogenic microorganisms such as viruses, bacteria, fungi, parasites, and rarely, misfolded proteins known as prions. They can spread through droplets when an infected person cough or sneezes, animal or bug bites, contaminated food or water, faecal matter, sexual contact, from mother to foetus, blood transfusion, organ transplants, and other medical procedures. Infectious agents can also survive on inanimate surfaces or objects and the pathogen gains entry to the body when the person touches their mouth, nose, or exposed skin after touching the contaminated surface. Such surfaces or objects are known as fomites and common examples of these are doorknobs, phones, and clothing.

Depending on the pathogen, an infectious disease can spread easily from person to person or be entirely non-communicable. The severity of the illness also depends on the infectious agent and the health of the infected individual. The most significant infectious disease event in recent history is none other than the COVID-19 pandemic, an outbreak of a respiratory disease that was caused by a viral pathogen known as coronavirus.

Diagnostic tests for infectious disease can be as simple as a nasal or mouth swab or obtaining a blood, urine, stool, or saliva sample. Some will require imaging scans like X-rays, MRIs or obtaining a tissue sample through a biopsy. The treatment for infectious diseases also depends heavily on the type of infectious agent. Infectious disease doctors are specially trained in the identification, treatment, and prevention of these illnesses. Infectious disease doctors work closely with other healthcare providers, epidemiologists, and scientists in controlling outbreaks, developing vaccines, and implementing preventive measures.

List of conditions
  1. Viruses
    1. COVID-19, a form of severe acute respiratory syndrome (SARS) caused by coronavirus
    2. Common cold, caused most commonly by rhinovirus, but may be caused by over 200 types of viruses
    3. The flu, caused by influenza virus
    4. Hand, foot, and mouth disease (HFMD), a disease caused by enteroviruses that often causes outbreaks in schools and childcare centres
    5. Chicken pox, caused by varicella-zoster virus
    6. Dengue fever, a disease spread through mosquito vectors that carry the dengue virus
    7. Stomach flu (gastroenteritis), caused by enteric viruses such as norovirus, rotavirus, adenovirus
    8. Respiratory syncytial virus (RSV), a seasonal disease that can be fatal in infants
    9. Hepatitis, the inflammation of the liver caused by hepatitis viruses
    10. Oral and genital herpes caused herpes simplex virus
    11. HIV/AIDS, an acquired immunodeficiency disease caused by human immunodeficiency virus
    12. Viral meningitis, an inflammation of the brain and spinal cord caused most commonly by enteroviruses and herpes simplex viruses
  2. Bacteria
    1. Strep throat, a throat and tonsils infection caused by group A Streptococcus spp.
    2. Tuberculosis (TB), caused by Mycobacterium tuberculosis
    3. Whooping cough (pertussis), caused by Bordetella pertussis
    4. C. diff infection, caused by Clostridioides difficile, an opportunistic gut bacterium that is usually kept under control by a healthy immune system
    5. MRSA, caused by Staphylococcus aureus that is resistant to a wide spectrum of antibiotics
    6. Sexually transmitted disease such as chlamydia, gonorrhoea, syphilis
    7. Urinary tract infections (UTIs)
    8. Tetanus, also known as lockjaw, an infection caused by Clostridium tetani
    9. Food- or waterborne illnesses caused by bacteria like Salmonella spp., Escherichia coli, Vibrio cholerae
    10. Plague, a disease that also infects animals that is caused by Yersinia pestis
    11. Legionnaires’ disease, caused by Legionella spp. and spreads through contaminated water
    12. Bacterial meningitis, more severe than viral meningitis and caused by over 50 types of bacteria
  3. Fungi
    1. Candidiasis, caused by the yeast Candida albicans and includes illnesses like thrush, vaginal yeast infections, and some diaper rash
    2. Ringworm (dermatophytosis), causes infection in the feet (athlete’s foot), groin and inner thighs (jock itch), and scalp
    3. Onchomycosis, a fungal infection of the nails
    4. Aspergillosis, caused by Aspergillus spp.
  4. Parasites
    1. Malaria, spread by mosquito vectors
    2. Toxoplasmosis, caused by Toxoplasma gondii which can be contracted from cat droppings
    3. Giardiasis, caused by Giardia intestinalis
    4. Hookworm
    5. Pinworm
  5. Prions (proteinaceous infections particle)
    1. Creutzfeldt-Jakob disease (CJD), a fatal degenerative brain condition
List of treatment/procedures
  1. Antibiotics, antiviral, antifungal, antiparasitic medication are used to treat bacterial, viral, fungal, and parasitic infections, respectively. Antibiotics, antifungals, and antiparasitics work by directly attacking the pathogen while antiviral drugs work by blocking the virus from binding to and entering your cells.
  2. Vaccines are administered preventatively and are made up off weakened or inactive infectious agents and they train your immune system to produce antibodies so that you can fight of the live pathogen during future infections.
  3. Some treatment forms focus on treating symptoms and boosting the immune system so that your body can fight off an infection naturally. Symptomatic treatment is often used for viral infections where antiviral drugs or vaccines are unavailable.

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